Anti-CANX, DyLight®633

Catalog #
AB41633
Family
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Category
Antibodies
Source
Goat
Application
WB, IHC (F), IF
Reactivity
Human, Rat, Mouse, Canine
Description
Goat polyclonal to CANX (Calnexin) - endoplasmic reticulum (ER) membrane marker conjugated to DyLight® 633. CANX is a member of the calnexin family of molecular chaperones. This protein is a calcium-binding, ER-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
Alternative names
Calnexin, CALX, CNX, FLJ26570, histocompatibility complex class I antigen binding protein p88, IP90, major histocompatibility complex class I antigen-binding protein p88, MS952, P90 antibody.
Immunogen
Purified recombinant peptide within residues 550 aa to the C-terminus of human CANX produced in E. coli.
Storage
Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
Form
Polyclonal antibody supplied as a 100 µl (2.5 mg/ml) aliquot in PBS, 20% glycerol, 0.05% ProClin® and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Concentration
2 mg/ml
Specificity
Detects a band of 90 kDa by Western blot whole cell lysates.
Special instructions
Avoid freeze/thaw cycles.

Usage

Application Values
WB 1:500-1:5,000
IF 1:50-1:500
IHC (F) 1:200-1:1,000

Reactivity Chart

Sample WB IHC (F) IHC (P) IF ELISA
Human +++ +++ ND +++ ND
Rat +++ +++ ND +++ ND
Mouse +++ +++ ND +++ ND
Canine +++ +++ ND +++ ND

Images

Anti-CANX Ab conjugated to DyLight@633 at 1/2,000 dilution using cell lysates at 40 µg per lane;

350 €

Quantity / Unit Size

250 µg
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